Top 5 healthcare practice management software solutions for 2025

Managing a healthcare practice in 2025 means juggling admin, compliance, and patient expectations, all while staying efficient. Practice management software is no longer optional. The best solutions in 2025 go beyond basic scheduling and billing- they integrate with electronic health records (EHRs), improve compliance, and streamline workflows.

Here’s a look at five widely used healthcare practice management software options shaping how care gets delivered in 2025.

1. Athenahealth

Athenahealth is a cloud-based practice management system that connects well to electronic health records (EHR) and revenue cycle management tools. It offers a user-friendly interface and robust analytics, helping practices optimize scheduling, billing, and patient engagement. Athenahealth’s focus on interoperability makes it a good fit for both large groups and smaller offices using different systems.

Key Highlights:

• Cloud-based and plays well with other EHR systems
• Advanced analytics for better decision-making
• Comprehensive revenue cycle management
• Includes patient engagement and scheduling tools

2. Epic

Epic is one of the most widely used EHR and practice management solutions in the United States, particularly among large healthcare organizations and hospital systems. It offers a comprehensive suite of features, including appointment scheduling, telehealth capabilities, and automated billing. Implementation can be complex and expensive, but for large systems needing customization and scalability, it’s one of the most capable options.

Key Highlights:

• • Ideal for large healthcare systems and hospitals
  • Advanced customization and scalability
  • Integrated telehealth and patient portal
  • Automated billing and workflow optimization

If managing foot traffic feels harder than it should, WaitWell makes it simple.

Learn how it works

3. AdvancedMD

Designed for independent practices and small to mid-sized healthcare providers, AdvancedMD offers a fully integrated practice management and EHR system. Its cloud-based platform provides features such as appointment reminders, telemedicine, and revenue cycle management. Reporting tools are customizable, and the interface is relatively easy to learn..

Key Highlights:

• Cloud-based for flexibility and accessibility
• Telemedicine integration for remote care
• Customizable reporting and analytics
• Strong revenue cycle management tools

4. Tebra

Tebra is used by small practices and urgent care centers, offering a straightforward, easy-to-use platform for managing billing, patient scheduling, and documentation. It is particularly well-suited for independent medical providers seeking affordable and effective solutions. Tebra’s cloud-based approach means providers can access it remotely, which suits teams that work across multiple locations or offer after-hours care..

Key Highlights:

• Affordable and easy to use for small practices
• Cloud-based for remote access
• Integrated billing and patient scheduling
• Simplified documentation and charting

5. DrChrono

DrChrono is an all-in-one practice management software designed with small to mid-sized practices. With features like customizable medical forms, electronic prescribing, and patient check-in tools, DrChrono helps streamline daily operations. Its mobile-friendly design allows healthcare professionals to manage appointments and patient records from iPads and smartphones, enhancing flexibility and efficiency.

Key Highlights:

• Mobile-friendly with iPad and smartphone support
• Customizable medical forms and e-prescribing
• Efficient patient check-in tools
• Integrated billing and claims management

Enhancing your practice with WaitWell

While these platforms cover billing, scheduling, and records, they don’t always manage the waiting room, physical or virtual. That’s where WaitWell steps in.

From check-in to room assignment, WaitWell helps practices reduce front-desk workload, improve wait time visibility, and prepare patients before they arrive. Patients can join a queue or book an appointment from your website, via QR code, or on-site tablets. They can complete intake forms, upload ID or insurance, and get automated instructions before seeing a provider.

“The more fields you add here, the more information you’ll have in advance of the patient’s arrival,” says Heather from the WaitWell team in this video demoing how WaitWell can be transformative for busy clinics, diagnostic centers or hospitals. “This ensures that every patient is prepared for their appointment beforehand, and staff don’t have to transfer information manually.”

WaitWell can integrate with your practice management system so data flows cleanly so there’s no duplicate entry, and no need for clipboards. Its queue screen handles both walk-ins and appointments in real-time. No-shows can be dealt with through automatic backfilling with available patients. Drag-and-drop tools let staff assign rooms without confusion.

You also get dashboards, daily summaries, and pre-built reports to monitor wait times, appointment types, and patient throughput, all in real time.

If your current software runs the back office, WaitWell gives you front-of-house control, without overcomplicating your tech stack.